| Place of Origin: | China |
|---|---|
| Brand Name: | HNB |
| Certification: | ISO |
| Model Number: | Urolithin A |
| Minimum Order Quantity: | 1KG |
| Price: | Negotiable |
| Packaging Details: | Aluminum foil bag |
| Delivery Time: | Usually7-10days |
| Payment Terms: | L/C, D/A, D/P, T/T, Western Union, MoneyGram |
| Supply Ability: | 5000kg/Month |
| CAS: | 123-99-9 | MF: | C9H16O4 |
|---|---|---|---|
| Specification: | 99% | MW: | 188.221 |
| Appearance: | White Powder | EINECS: | 204-669-1 |
| High Light: | Urolithin A Dietary Supplements Ingredients,Urolithin A Powder Anti Aging,Dietary Supplements Ingredients CAS 1143-70-0 |
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Anti-Aging Dietary Supplements Ingredients CAS 1143-70-0 Urolithin A Urolithin B
| Prodcut name | Urolithin A |
| MOQ | 1KG |
| CAS No. | 1143-70-0 |
| Appearance | White powder |
| Molecular Formula | C13H8O4 |
| Molecular Weight | 228.20000 |
| Assay | 99% |
What is urolithin A?
Urolithin A is a product of intestinal flora From the name, it may make you wonder, is it related to stones? But it's completely unrelated. Urolithin A, also known as Urolithin A (UA), has nothing to do with the kidneys. It is a metabolite of gut microbes and cannot be directly supplemented from food. The raw materials of UA can only be obtained from food, and it is not necessary to eat more foods containing UA precursors to synthesize more urolixin A, depending on the composition of the gut flora.
What is the bioavailability of urolitin related to?
Seeing this, you may already know what UA bioavailability is related to.The most important thing is the composition of the microbiome, because not all microbial species can be produced. The raw material for UA is ellagitannin, a precursor obtained from food, which is readily available and almost ubiquitous in nature.
Ellagitannin hydrolyzes in the intestine to release ellagic acid, which is further processed by the intestinal flora into urolithin A. As for which gut bacteria synthesize UA in particular? Unfortunately, there is no definitive conclusion.According to the results of A study in the journal Cell, only 40 percent of people can naturally convert from the precursor to usable urolixin A.Other benefits of urolixin A Urolixin A can do a lot more than we thought. Help with weight loss Urolixin A not only protects muscles, but the latest study found that urolixin A can actually affect cellular lipid metabolism and fat production.
Urolixin A activates mitochondrial autophagy Urolithin A's protection against muscle loss is relatively recent, and previous studies of it have focused on mitochondria, particularly mitochondrial autophagy. (Mitochondrial autophagy refers to the selective removal of damaged mitochondria by autophagosomes) UA can activate mitochondrial autophagy through various ways, such as activating enzymes that promote mitochondrial autophagy, regulating mitochondrial autophagy pathways, and promoting the formation of autophagosomes.
(Schematic diagram of mitochondrial autophagy pathway activated by urolithin A (UA)) Now everyone should be familiar with autophagy, mitochondrial autophagy is one of them, refers to the removal and recycling of old or waste mitochondria. With age and some age-related diseases, mitochondrial autophagy declines or even stalls, and organ function slowly declines.
The Introductction of Urolithin A :
Urolithin A is produced by gut flora and is a natural metabolite of a class of compounds called ellagitannins that are found in pomegranates and some other fruits and nuts. Related studies have shown that urolithin A is a powerful intestinal metabolite that can restore mitochondria and reverse muscle aging.
The Function of Urolithin A :
1.Urolithin A is not known to be found in any food source. Its bioavailability mostly depends on individual microbiota composition, as only some bacteria are able to convert ellagitannins into urolithins.
2.Urolithin A belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).
